Efficacy of a fixed combination of ciclesonide and formoterol: The EXCITED-study

Posted by: admin on: October 28, 2011

Recent study suggests the same efficacy of newer combination of ciclesonide and formoterol as of fluticasone and salmeterol.


Recommended treatment for moderate to severe asthma is the combination of an inhaled corticosteroid and a long-acting beta2-agonist. The present study was designed to evaluate the efficacy of a newly developed fixed combination of ciclesonide and formoterol in comparison to the marketed fixed combination of fluticasone and salmeterol in patients with moderate asthma.

A significant improvement from baseline in lung function, symptom score and rescue medication use was observed in both groups at all time points. No differences were observed between treatments in the frequency of adverse events and overnight urinary cortisol/creatinine ratio. The studied fixed combination of ciclesonide/formoterol is not inferior to the marketed fixed combination of fluticasone/salmeterol in terms of efficacy and tolerability.

Reference: http://www.docguide.com/efficacy-fixed-combination-ciclesonide-and-formoterol-excited-study?hash=80445d1a&eid=22199&alrhash=2efbb8-880279c42369cc2f8adcb48a6daaf3d2

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