Stepping down asthma treatment: how and when

Posted by: admin on: February 21, 2012

Maintenance treatment of chronic asthmatic patients has been a challenge to most family clinicians and physicians. Here is a guideline suggested by the experts.

Team@CMHF

Guidelines suggest that asthma medication should be reduced once asthma control is sustained. Moderate-dose inhaled corticosteroids (ICS) can typically be reduced, but questions remain about the lowest effective ICS dose and the role of non-ICS controllers in treatment reduction. Long-acting beta agonist (LABA) safety concerns have created controversy about how to step down patients on ICS/LABA therapy. This review will focus on the current status of these issues.

RECENT FINDINGS: Intermittent ICS treatment, often in fixed combination with short-acting beta agonist, is an emerging strategy for control of mild asthma. Addition of leukotriene modifiers, LABAs, and omalizumab to ICS can allow for reduced ICS dosing. Doses of ICS that control symptoms may be inadequate to control exacerbations. Reducing ICS dose before discontinuing LABAs may be the more effective approach for patients on combination therapy.

SUMMARY: Use of non-ICS controllers allows for ICS dose reduction with superior outcomes. Tapering of ICS prior to LABA discontinuation may be the favored approach for patients on ICS/LABA therapy, but an understanding of long-term outcomes and further safety data are required. The lowest ICS dose that adequately controls both asthma impairment and risk remains to be determined.

Ref: http://www.docguide.com/stepping-down-asthma-treatment-how-and-when?hash=80445d1a&eid=23294&alrhash=2efbb8-880279c42369cc2f8adcb48a6daaf3d2

Leave a Reply

Your email address will not be published. Required fields are marked *

*

CMHF Accredited by Maharashtra Medical Council

Subscribe to our Posts

Enter your email address:



  • drchasrani: Difficult to get such a data, authenticated at that. Try Times of India online library
  • rakesh pore: hi, where can i get genuine information about "10 most common drugs sold in india?" i want it for a local project
  • nilesh dutta: sir, Plz give detail about MBA Sports Management Thanks and Regards

Calculate Your Body Mass Index



Check your Body Mass Index »

    Cherry - 60 kcal in 100g
    60kcal
    Cherry - 60 kcal in 100g
    by Noni