Ondansetron used during chemotherapy has been found to cause arrhythmia. Here are a few lines about this statement.

Team@CMHF

A drug used to treat nausea and vomiting caused by chemotherapy may trigger dangerous and possibly lethal changes in heart rhythms, the FDA warned.
The drug, ondansetron (Zofran), may increase the risk of “developing prolongation of the QT interval of the electrocardiogram, which can lead to an abnormal and potentially fatal heart rhythm, including Torsade de Pointes,” the FDA said.

Ondansetron is a 5-HT3 serotonin receptor antagonist, commonly prescribed to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery.
The FDA said it has ordered GlaxoSmithKline, which markets Zofran, to conduct a thorough QT study to determine the degree to which the drug may cause QT interval prolongation. The agency expects the results next summer.

In the interim, the FDA has ordered that the drug’s label be changed to include “a warning to avoid use in patients with congenital long QT syndrome ”
The label will also recommend ECG monitoring in certain patients.

Ref:  http://www.medpagetoday.com/HematologyOncology/Chemotherapy/28538?utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=WC&eun=g333280d0r&userid=333280&email=drchasrani@cmhs.in