The control of hypertension with perindopril amlodipine combination far supersedes, the so far considered effective combination of atenenol and diuretic. Here is the new study.

Team@CMHF

Treatment of hypertension is fundamental for the prevention of cardiovascular events and mortality. This review focuses on the specific benefits of the ACE inhibitor perindopril.

A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension. Good tissue penetration, strong affinity for ACE and a long duration of action support the dose-dependent blood pressure lowering efficacy. Perindopril in combination with amlodipine significantly reduced total and cardiovascular mortality as compared to atenolol/diuretic in large-scale clinical trials of hypertensive patients

Expert opinion: Perindopril is effective and safe for blood pressure control with a dose-dependent effect. Combination therapy with indapamide or amlodipine reduces cardiovascular events and mortality in hypertensive patients. Pharmacological proprieties and results of clinical trials support the choice of perindopril as an appropriate treatment for hypertensive patients.

Ref: http://www.docguide.com/perindopril-treatment-hypertension?hash=80445d1a&eid=20240&alrhash=2efbb8-880279c42369cc2f8adcb48a6daaf3d2

For: Allopaths