Kidney Risk Higher in Diabetic Women than Men

Posted by: admin on: March 12, 2012

Here is a finding which alerts the doctors dealing with female diabetics, to maintain strict sugar levels and take great care in their management.


PHILADELPHIA — Among patients with type 2 diabetes, women were more likely to have risk factors for chronic kidney disease than men, which may also put them at risk for poorer outcomes, researchers found.

At baseline, diabetic women were more likely to be obese, to have high LDL cholesterol, and to have an estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m2, according to Margaret Yu, MD, of the University of Washington in Seattle. Through five years of follow-up, they were also more likely to progress to a higher stage of chronic kidney disease and to progress to end-stage renal disease , although mortality rates were similar between the sexes after accounting for diabetes-related complications, Yu reported There was some evidence that women did not receive the same quality of care as men, as they were less likely to have their cholesterol checked and to get a statin. Yu said there is this overall perception that women aren’t as at risk for chronic kidney disease.”

To explore the issue, she and her colleagues examined data from 4,839 ambulatory patients with type 2 diabetes (49% female) who were enrolled in a Seattle HMO.

After five years of follow-up, women had poorer outcomes on average, even after adjustment for baseline stage of chronic kidney disease. Yu said that she and her colleagues will soon be collecting 10-year follow-up data, which might be more informative than the five-year data because of the time it takes to progress to end-stage renal disease.
She also plans on conducting a survival analysis to account for the higher mortality among men.


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