Exercise and fractures in postmenopausal women: 12-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)

Posted by: admin on: June 17, 2011

This trial is the first exercise study that focuses on fracture incidence as a primary study endpoint. Findings further increased the evidence that exercise relevantly prevents fractures in the elderly.

INTRODUCTION: The purpose of this study is to determine the effect of strictly supervised long-term exercise training on “overall” fracture incidence and bone mineral density (BMD) in postmenopausal osteopenic women.

METHODS: Eighty-five early postmenopausal (1-8 years), osteopenic women living in the area of Erlangen-Nuremberg, Germany without any medication or diseases affecting bone metabolism were assessed after 12 years of supervised exercise (EG) or unvarying lifestyle (control, CG). Exercisers were encouraged to perform two group sessions/week and two home training sessions/week. Calcium and vitamin D supplementation was provided for both groups. “Overall” fractures were determined by questionnaires and structured interviews. The BMD was assessed at lumbar spine and proximal femur by dual-energy X-ray absorptiometry.

CONCLUSION: Although we marginally failed to determine significant effects on overall fracture risk or rate ratio, our study increased the body of evidence for the fracture prevention efficiency of exercise programs, with special regard on bone strength (as assessed by bone mineral density measurement). Future studies should focus on subjects more prone to fractures to generate enough statistical power to clearly determine this issue.

Ref: http://www.docguide.com/exercise-and-fractures-postmenopausal-women-12-year-results-erlangen-fitness-and-osteoporosis-preven?hash=80445d1a&eid=20362&alrhash=2efbb8-880279c42369cc2f8adcb48a6daaf3d2

For: Allopaths

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