The fast track life we lead now has caused a rise in psychiatric cases & generalized anxiety is one of them. Of the many drugs used Fluoxetine and sertraline seem to be the 2two best drugs. This is how it goes.

Team@CMHF

Objective: To appraise the evidence for comparative efficacy and tolerability of drug treatments in patients with generalized anxiety disorder.

Eligibility criteria Double blind placebo controlled randomized controlled trials; published systematic reviews and meta-analyses of randomized controlled trials. Randomized controlled trials including adult participants (aged ≥18) receiving any pharmacological treatment for generalized anxiety disorder

Analyses compared nine drugs (duloxetine, escitalopram, fluoxetine, lorazepam, paroxetine, pregabalin, sertraline, tiagabine, and venlafaxine).

Conclusions: Though the frequentist analysis was inconclusive because of a high level of uncertainty in effect sizes (based on the relatively small number of comparative trials), the probabilistic analysis, which did not rely on significant outcomes, showed that fluoxetine (in terms of response and remission) and sertraline (in terms of tolerability) seem to have some advantages over other treatments. Among five UK licensed treatments, duloxetine, escitalopram, and pregabalin might offer some advantages over venlafaxine and paroxetine.

Ref: http://www.docguide.com/efficacy-drug-treatments-generalised-anxiety-disorder-systematic-review-and-meta-analysis

For: Allopaths