International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women

Posted by: admin on: May 6, 2011

Urinary symptoms abound, especially in women; a large percentage self medicating with entry level (or higher) quinolone (just a few tablets; never a course). With increasing instance of pyelonephritis induced CRF in young women, it is time we took notice of how such infections are to be treated.


A Panel of International Experts was convened to update the 1999 Uncomplicated Urinary Tract Infection Guidelines The focus of this work is treatment of women with acute uncomplicated cystitis and pyelonephritis, diagnoses limited in these guidelines to premenopausal, non-pregnant women with no known urological abnormalities or co-morbidities. The issues of in vitro resistance prevalence and the ecological adverse effects of antimicrobial therapy (collateral damage) were considered as important factors in making optimal treatment choices and thus are reflected in the rankings of recommendations.


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