Antidepressant agents increase the risk of type 2 diabetes

Posted by: admin on: January 31, 2012

Antidepressant useage is on the rise.A study proves that long term use of antidepressants increase the chances of acquiring Type 2 diabetes.

Team@CMHF

PURPOSE: To determine whether there is an association between antidepressant use and the risk of developing type 2 diabetes.

METHODS: This study was a retrospective cohort analysis using the Texas Medicaid prescription claims database. Data were extracted for new users of either antidepressant agents (exposed) or benzodiazepines (unexposed) from January 1, 2002 through December 31, 2009. Patients aged 18-64 years without a prior history of diabetes were included.

RESULTS: Among the total study population the majority were in the exposed versus the unexposed group. A total of 2,943 patients (6.6%) developed type 2 diabetes during the follow-up period. Antidepressant use was associated with an increase in the risk of diabetes when compared to benzodiazepine use. The association was observed with tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, selective serotonin reuptake inhibitors and “other” antidepressants.

CONCLUSIONS: The results of this study suggest that antidepressant use is associated with an increased risk of diabetes. This association was observed with use of TCAs, SNRIs, SSRIs, and “other” antidepressants.

Ref: http://www.docguide.com/use-antidepressant-agents-and-risk-type-2-diabetes?hash=80445d1a&eid=23536&alrhash=2efbb8-880279c42369cc2f8adcb48a6daaf3d2

 

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